abstract：:This report provides specific information on the prevalence rates of the most common side effects during the first 3 cycles of use of 3 combination oral contraceptives (OCs) containing 50 mcg estrogen. The probabilities of a symptom occurring for the first time, or persisting once present, during the initial cycles of...

journal_title：Contraception

authors： Berger GS,Edelman DA,Talwar PP

更新日期：1979-11-01 00:00:00

abstract：:To study the effect of Stryphnodendron polliphyllum M. upon implantation, the seeds and empty pods of this plant were given to pregnant rats, on the 5th and 6th days of gestation. The animals were sacrificed on the 14th day of pregnancy and implantation and resorption indices were studied. The results show definite em...

journal_title：Contraception

authors： Guerra MO,Araujo FC,Peters VM,Andrade AT

更新日期：1979-10-01 00:00:00

abstract：:The incidence of Candida albicans (C.A.) infection of the vagina was evaluated in vaginal discharges obtained from 85 subjects using a large battery of culture media and confirmatory tests. Twenty women using DMPA 150 mg i.m. contraceptive injections for more than one year (long-term users) were compared with forty 2n...

journal_title：Contraception

authors： Toppozada M,Onsy FA,Fares E,Amir S,Shaala S

更新日期：1979-08-01 00:00:00

abstract：:The concentration of FSH, LH, testosterone and sperm agglutinating and cytotoxic antibodies have been determined in 87 men at varying time intervals after vasectomy. The results indicated that vasectomy is not associated with statistically significant changes in any of these parameters. Furthermore, no correlation exi...

journal_title：Contraception

authors： Tyler JP,Richardson DW,Newton JR

更新日期：1979-06-01 00:00:00

abstract：:In order to determine whether inhibition of the endometrial estradiol-17 beta-dehydrogenase activity by Cu++ could be one of the factors accounting for the enhanced contraceptive efficacy of copper intrauterine devices (Cu-IUD), the activity of the enzyme was measured in endometrial biopsies from women wearing this de...

journal_title：Contraception

authors： Tseng L,Dramusic V,Gurpide E

更新日期：1979-03-01 00:00:00

abstract：:Subcutaneously administered implant-D containing 40 mg of Norethindrone acetate in a single silastic implant was offered to 79 subjects who desired spacing of their family. The effect of constant release of steroid from this device on metabolic and endocrine functions was studied. Each subject in the pretreatment stat...

journal_title：Contraception

authors： Shahani SM,Kulkarni PP,Bhate PA,Patel KL

更新日期：1979-02-01 00:00:00

abstract：:A randomized comparative study between Nova-T and Copper-T-200 was performed simultaneously in Denmark, Finland and Sweden. The results of 741 postmenstrual insertions with Nova-T and 780 with Copper-T are reported. The pregnancy rate of Nova-T was lower in every age and parity group. The pregnancy rate of Copper-T-20...

journal_title：Contraception

authors： Luukkainen T,Nielsen NC,Nygren KG,Pyörälä T,Allonen H

更新日期：1979-01-01 00:00:00

abstract：:The Indian Council of Medical Research initiated a multicentric trial with prostaglandins in 1976 to assess the safety and efficacy of their use in midtrimester abortions. PGF2 alpha and 15-Me-PGF2 alpha were compared using the intra-amniotic (I.A.) route. 15-Me-PGF2 alpha was also evaluated by extra-amniotic (E.A.) r...

journal_title：Contraception

authors： Tejuja S,Choudhury SD,Manchanda PK

更新日期：1978-12-01 00:00:00

abstract：:The importance of a simple, rapid and highly sensitive test for the diagnosis of early pregnancy cannot be overemphasized. In the present times when newer delivery systems of contraceptive agents and menstrual regulation procedures are increasingly used for fertility regulation, it is inevitable that confirmation of e...

journal_title：Contraception

authors： Shahani SM,Kulkarni PP,Patel KL

更新日期：1978-11-01 00:00:00

abstract：:Hepatic function in female rats given 200 microgram of quinestrol every 15 days for up to 210 days was studied. Prolonged treatment with quinestrol affected liver weight, serum cholestrol levels, biliar flux, and bromosulphthalein test, but these parameters tended toward control levels after 30 days of treatment. Quin...

journal_title：Contraception

authors： Gioia IA,Lencioni LJ,Koch OR

更新日期：1978-09-01 00:00:00

abstract：:Twenty patients undergoing elective midtrimester abortion by urea amnioinfusion had bacteriologic culture data obtained before and after the procedure. Despite the presence of pathogens in the vagina and cervix prior to the procedure, only 20% of patients exhibited endometrial growth following abortion. Factors that s...

journal_title：Contraception

authors： Burkman RT,Spence MR,Atienza MF,King TM

更新日期：1978-06-01 00:00:00

abstract：:The effect of a single implant-D containing 40 mg of norethindrone acetate on the endometrium and serum progesterone, and its mode of contraceptive action was investigated. 20 women aged 20-40 (parity 1-5) had used implant-D for periods of 7-27 months. Endometrial biopsies and peripheral venous bloods were collected...

journal_title：Contraception

authors： Takkar D,Jeyaseelan S,Kinra G,Laumas KR,Hingorani V

更新日期：1978-02-01 00:00:00

abstract：:Zona-free hamster oocytes were used to evaluate the entry of human spermatozoa into the oocytes. Suspensions of spermatozoa, free of seminal plasma, were preincubated for varying periods in a modified Tyrode's solution under mineral oil. Zona-free hamster oocytes were prepared and added to the sperm suspension for f...

journal_title：Contraception

authors： Barros C,Gonzélez J,Herrera E,Bustos-Obregón E

更新日期：1978-01-01 00:00:00

abstract：:Levels of contraceptive steroids in breast milk and plasma of lactating women were investigated. 7 lactating women received 150 mg medroxyprogesterone acetate (MPA) 1 week after delivery. 5 women (lactating) took 350 mcg norethisterone (NET) and 2 took 150 mcg d-norgestrel (d-ng) + 30 mcg ethinyl estradiol. Milk an...

journal_title：Contraception

authors： Saxena BN,Shrimanker K,Grudzinskas JG

更新日期：1977-12-01 00:00:00

abstract：:The effect of 2 long-acting injectables on the plasma protein-bound carbohydrate components and serumucoid when taken for different periods, was illustrated in 100 women of childbearing age. 40 acted as controls, 30 took depot-medroxyprogesterone acetate (DMPA), and 30 took norethisterone enanthate (NET-EN). DMPA wa...

journal_title：Contraception

authors： Saleh FM

更新日期：1977-10-01 00:00:00

abstract：:The efficacy and side effects of a new synthetic compound, 16-phenoxy-W-17, 18, 19, 20-tetranor prostaglandin E2 methylsulfonylamide, for menstrual induction. The study was conducted in an outpatient clinic in 240 patients with a delay in menstruation of 6-14 days. In 206 patients (86%) the immunologic pregnancy tes...

journal_title：Contraception

authors： Karim SM,Rao B,Ratnam SS,Prasad RN,Wong YM,Ilancheran A

更新日期：1977-10-01 00:00:00

abstract：:A new synthetic progestagen, Org 2969 (13-ethyl-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-17-ol) was administered to 9 healthy normally menstruating women. 3 subjects (Group 1) ingested .030 mg, while 6 (Group 2) ingested .015 mg of the compound daily on Days 1-20 of 1 menstrual cycle. The previous menstrual...

journal_title：Contraception

authors： Viinikka L,Hirvonen E,Ylikorkala O,Nummi S,Virkkunen P,Ranta T,Alapiessa U,Vihko R

更新日期：1977-07-01 00:00:00

abstract：:The metabolism of isotopically labeled ethinyl estradiol (EE) and mestranol (ME) was studied in 3 baboons before and after the simultaneous injection of a norethindrone-mestranol contraceptive formulation. 6 days after the administration of tritiated-EE and carbon-14-ME, the mean urinary excretion of labeled-EE was 3...

journal_title：Contraception

authors： Kulkarni BD,Avila TD,O'Leary JA

更新日期：1977-03-01 00:00:00

abstract：:The effects of cyproterone acetate (CPA), administered orally in dos es of either 10 or 20 mg/day for 26 weeks, were studied in 15 healthy male volunteers. During treatment, there was a decrease in sperm density and in normal-shaped sperm and an increase in pathological and immature forms, an increase in dead spermat...

journal_title：Contraception

authors： Koch UJ,Lorenz F,Danehl K,Ericsson R,Hasan SH,Keyserlingk DV,Lübke K,Mehring M,Römmler A,Schwartz U,Hammerstein J

更新日期：1976-08-01 00:00:00

abstract：:Test agents were selected because of previous evidence of contragestationaal activity when administered systemically or because of known local effects which would be likely to cause endometrial changes having an adverse effect on pregnancy. A group of virgin female Sprague-Dawley rats were treated on Day 3 of pregnan...

journal_title：Contraception

authors： Conner EA,Blake DA,Parmley TH,Burnett LS,King TM

更新日期：1976-05-01 00:00:00

abstract：:The effect of cupric ions on the uptake of tritiated-thymidine and 5-tritiated-uridine into endometrial cells obtained from pseudopregnant rabbits was studied in vitro. In endometrial cells obtained 48 and 120 hours after human chorionic gonadotropin injection, the uptake of tritiated-thymidine was significantly inhi...

journal_title：Contraception

authors： Grundsell H,Håkansson L

更新日期：1975-10-01 00:00:00

abstract：:The effect of propanolol hydrochloride (PH) and oxprenolol hydrochloride (OH) on ovulation was studied in mature rabbits. PH-treated animals did not accept mating and ovulation was suppressed after forced mating. 5 of 6 OH-treated animals refused mating. No implantation sites or corpora lutea were found in the anim...

journal_title：Contraception

authors： Foda MS,Darwish NA,Shafeek AA,Sharaf EM,Zaki MA

更新日期：1975-07-01 00:00:00

abstract：:Biochemical studies with a once-a-month contraceptive pill containing 2 mg quinestrol and 2.5 mg quingestanol acetate were undertaken during a period of 24 months. The 1st pill was given on the 2nd day of the menstrual cycle and the 2nd on the 22nd day of the same cycle; thereafter the pills were given every 28th day...

journal_title：Contraception

authors： Donde UM,Virkar KD

更新日期：1975-06-01 00:00:00

abstract：:This study examines the efficacy and side effects of 15-methyl-prostaglandins F2alpha (PGF2a) free acid administered intramuscularly for midtrimester abortion. 50 healthy women aged 14 to 37 years and between 12 to 18 weeks gestation were randomly selected from the abortion clinic at the Los Angeles County/USC Medica...

journal_title：Contraception

authors： Slaughter L,Ballard CA

更新日期：1975-05-01 00:00:00

abstract：:The influence of oral contraceptives (OCs) on sex hormone binding globulin (SHBG) capacity was studied in women using OCs for a at least 2 months and compared with values in normal menstruating women, in pregnant women, in postmenopausal women, and in normal males. Binding capacity was measured by ammonium sulfate p...

journal_title：Contraception

authors： van Kammen E,Thijssen JH,Rademaker B,Schwarz F

更新日期：1975-01-01 00:00:00

abstract：:Differential precipitation of plasma proteins after equilibration of the plasma with tracer amounts of testosterone (T) was used to measure free and not-T-estradiol binding globulin (TeBG)-bound T in 20 women and 10 men. Tritiated T was the tracer used. Comparison of this method with the equilibration dialysis metho...

journal_title：Contraception

authors： Tremblay RR,Dube JY

更新日期：1974-12-01 00:00:00

abstract：:A moderately effective oral progestogen contraceptive, R-2323 (13beta-ethyl-17alpha-ethynyl-17-hydroxy-gona-4,9,11-trien,3-one), was administered weekly in doses of 2.5 mg and 5 mg to 5 subjects each for 8 weeks. In 2 of the 10 treatment cycles of 2.5 mg and 4 of the 10 treatment cycles of 5 mg, progesterone levels i...

journal_title：Contraception

authors： Tredway DR,Mishell DR Jr

更新日期：1974-08-01 00:00:00

abstract：:20 patients underwent intraamniotic administration of PGF2alpha for termination of pregnancies ranging from 14-20 weeks gestation. Success was achieved in 18 patients (90%) with this method. The 2 failures were terminated vaginally with adjunctive use of intracervical laminaria and intravenous pitocin induction. 10...

journal_title：Contraception

authors： Berman R,Hale RW,Reich LA,Pion RJ

更新日期：1974-06-01 00:00:00

abstract：:A study was undertaken to determine if copper wire, placed within the uterine lumen after implantation and kept in situ throughout pregnancy, results in an excessive accumulation of the metal in maternal and/or fetal tissues; and if so, what effect if any, such an accumulation may have on both mother and offspring. ...

journal_title：Contraception

authors： Moo-Young AJ,Tatum HJ

更新日期：1974-05-01 00:00:00

abstract：:Blood pyrodoxine hydrochloride (vitamin-B6) concentration was determined in 50 women using combined oral contraceptives (OCs), 24 women who received an intramuscular injection of 150 mg medroxyprogesterone acetate (MPA) every 12 weeks, and in 14 women who used an intrauterine device (IUD) at the out-patient contracep...

journal_title：Contraception

authors： Bennink HJ,Schreurs WH

更新日期：1974-04-01 00:00:00

abstract：:To test the contraceptive efficacy of norethindrone (NET), the effect of NET on peripheral plasma levels of progesterone and estradiol after ovulation was investigated, since low levels of ovarian steroids might affect the postovulatory endometrium and thereby impair normal blastocyst implantation. Two studies were ...

journal_title：Contraception

authors： Nygren KG,Johansson ED,Wide L

更新日期：1972-06-01 00:00:00